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Andriy Goy

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Open access Aug 2026

Rational design of multicomponent rivaroxaban solid dispersions using thermodynamic and statistical modeling

The aim. The aim of the work is to study the effect of hydrophilic polymers (PVP K-12, PVP K-17, HPC) and excipients (sucrose, mannitol) on rivaroxaban supersaturation, as well as to apply thermodynamic modeling to determine the optimal composition and evaluate the robustness of ternary solid dispersion systems (SDS)....

Volodymyr Fedorenko, O. Chornyi, V. Yaremenko et al. · 0 citations

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