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Andrey A. Bobkov

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Open access Oct 2026

Small-Molecule Modulators of HIPK4 Activity and Proteostasis

The discovery of a cyanoquinoline-based series of HIPK4 inhibitors with nanomolar potency is reported, establishing cyanoquinoline ligands as a new chemotype for probing HIPK4 biology and advancing male contraceptive discovery.

Zai-Le Zhuang, Riley K. Togashi, P. Kearney et al. · 0 citations

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