Andrés M. Escorcia

Multiscale Modeling of Lytic Polysaccharide Monooxygenases in Oxidized and Reduced Redox States

Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent oxidative enzymes whose catalytic activity depends on redox cycling of a single copper ion in the active site, coordinated by the conserved histidine brace motif. Although the static coordination geometry of the active site has been characterized crysta...