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Andrea D. Ordonez

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Review Open access Oct 2026

The Transposon Toolkit for Immune Isoform Diversity in Evolution and Disease

Transposable elements (TEs) occupy roughly half of the genomic content across mammals and have long been recognized for their contributions to immune gene regulation as co-opted enhancers and promoters. Less appreciated is their role in diversifying the immune transcriptome itself. TE sequences embedded in introns and...

Andrea D. Ordonez, Edward B. Chuong · 0 citations

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