Open access
Aug 2026
Fatty acid oxidation fuels mitochondrial respiration to drive epidermal stem cell fate and differentiation
Skin barrier function relies on the epidermis, whose integrity is maintained by basal stem cells that continuously renew and differentiate into a multilayered architecture. Disrupted epidermal differentiation underlies numerous hyperproliferative and inflammatory skin disorders. While transcriptional and epigenetic mec...
Kristina Todorova, S. Sol, F. Boncimino et al.
· Nature Communications · 0 citations