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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Anders Dahlén

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2 papers indexed here

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Open access Sep 2026

In Vitro Exploration of Antisense and Splice-Switching Oligonucleotide Multimers Using an Engineered Peptide Scaffold

Antisense oligonucleotides (ASOs) are potent therapeutics that enable precise RNA modulation. However, efficient delivery to tissues and cell types remains a major challenge. Multimerization, linking multiple ASOs to form large constructs, represents a promising strategy to explore delivery and pharmacokinetics modul...

Quentin Vicentini, Elena Grobecker, D. Daniele et al. · 0 citations
Open access Aug 2026

Dual recognition drives site-directed G-quadruplex stabilization: Oligonucleotide design in G4 ligand-oligonucleotide conjugates

G-quadruplex (G4) DNA structures are increasingly recognized for their roles in transcriptional regulation and genome stability, making them attractive therapeutic targets. Selective recognition of individual G4s remains challenging due to the high structural similarity among G4 motifs. G4 Ligand-Oligonucleotides conju...

Alva Abrahamsson, Sakina Khwaja, Namrata Chaudhari et al. · 0 citations

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