Open access
Sep 2026
Electrochemical DNA hairpin sensors for differentiating small molecule intercalation from minor groove binding
Small molecule double-stranded DNA intercalators have significant potential for therapeutic applications. However, screening for and confirming a drug candidate's intercalative behavior remains labor-intensive and costly. To address this, we investigated the sequence and biophysical parameters that affect the performan...
Kiara Thompson, K. Barnes, Saron P. Yoseph et al.
· Sensors & Diagnostics · 0 citations