Open access
Oct 2026
Cetuximab-loaded self-assembled polymeric nanoparticles for the integrin-targeted therapy of glioblastoma
The blood-brain barrier (BBB) restricts the delivery of therapeutic small-molecule and macromolecular drugs to the central nervous system and precludes the therapeutic application of monoclonal antibodies in glioblastoma (GBM). In this work, we investigate integrin-targeted polyelectrolyte complex nanoparticles for the...
D. Mishra, Marcelo Calderón, Ana Beloqui et al.
· JCIS Open · 0 citations