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Review Open access Sep 2026

CRISPR-based functional genomic screening in neurodegeneration: mechanistic insights into AD, PD, and ALS

Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), are characterized by pronounced clinical and molecular heterogeneity, as well as highly interconnected pathogenic pathways. This biological complexity has long hindered efforts to systemati...

Feng Xue, Li-Li Bao, An-Da He et al. · 0 citations

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