Author

Amit Sharma

2 papers indexed here

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Review Open access Oct 2026

The interplay of cGAS-STING and autophagy: bidirectional regulation and pathophysiological implication

The cGAS-STING pathway is a fundamental cytosolic DNA-sensing mechanism that activates innate immune responses through the production of type I interferons (IFNs) and other cytokines. Autophagy, a conserved intracellular degradation system, plays crucial roles in maintaining cellular homeostasis by clearing damaged o...

Dan-Dan Ye, Qiong Li, Amit Sharma et al. · Molecular Medicine · 0 citations

Open access Sep 2026

Leucine, autoimmune diseases, and circulating mediators shape the causal landscape of lymphoid malignancies

Introduction While genetic abnormalities underlying lymphoid malignancies (LM) are well-characterized, the environmental and metabolic determinants driving LM remain largely unexplored. Autoimmune diseases are known risks, yet the specific circulating mediators and potential protective dietary factors linking these con...

Dong-Guo Liang, Yan Ren, Yu-Qi Feng et al. · Frontiers in Immunology · 0 citations