Open access
Jul 2026
A detailed molecular picture of protein folding during active translation
A hydrogen-deuterium pulse-labeling approach is developed which reveals nascent polypeptide folding at a high level of structural detail and its kinetic coupling with translation and reveals diverse strategies that promote robust protein folding during non-equilibrium translation.
Amir Bitran, C. Bustamante, Susan Marqusee
· bioRxiv · 0 citations