Author

Amarish K. Yadav

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Open access Jul 2026

Target site and guide RNA multiplexing architecture shape homing gene drive efficiency in Drosophila suzukii

It is found that using more than one gRNA reduced the efficiency of inheritance, especially in females, and this results show that gene drive performance depends strongly on biological context and design choices, and that strategies must be carefully optimized in the target species.

Amarish K. Yadav, Weizhe Chen, Jackson Champer et al. · bioRxiv · 0 citations