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Author

Amar Ghosh

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2 papers indexed here

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Oct 2026

A Competing C-Terminal β-Turn Controls Frame-Dependent Stability of Collagen Triple Helices

Frame-dependent stability of collagen triple helices is well documented, but its structural origin remained unresolved. Here we identify a C-terminal β-turn-like conformational state with intramolecular CO···HN contacts as the competing motif governing this behavior. In POG-frame collagen mimetic peptides, a C-termin...

Aritra Naha, Amar Ghosh, Bani Kanta Sarma · 0 citations
Aug 2026

Kinetic Frustration of Collagen Folding Drives Condensate-Mediated Fibrous Assembly.

Collagen assembly is generally assumed to proceed hierarchically with rapid triple-helix folding preceding higher-order organization. Here, we show that this paradigm can break down when triple helix formation becomes kinetically frustrated. Using collagen-mimetic peptides containing cis-trans-isomerizing cationic and...

Debajit Kalita, Debashree Borah, Amar Ghosh et al. · 0 citations

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