Amany Belal

Vismodegib-loaded ufasomes inhaler for treatment of non-small cell lung cancer.

Invasomes nanocarriers for targeted delivery of letrozole derivative: A novel strategy to mitigate breast cancer.

As a non-steroidal aromatase inhibitor, letrozole is primarily used for treating estrogen-dependent breast cancer (BC). However, the long-term use of letrozole is limited due to severe adverse effects, including increased risks of cardiovascular disease and osteoporosis. A new bis-triazole compound derived from letrozo...

Ufasomal Nanocarriers for Enhanced Cardiac Delivery of Nifedipine: A Novel Strategy to Mitigate Doxorubicin-Induced Cardiotoxicity in Breast Cancer Therapy.

These findings establish the nasal NLU formulation as a promising therapeutic platform to mitigate doxorubicin-induced cardiotoxicity and exhibit superior cardioprotective and antioxidant performance over the oral NFP.