Next‐generation mouse models have transformed preclinical oncology by enabling detailed study of tumor initiation, progression, immune interactions, and metastasis. Traditional systems lacked tumor heterogeneity and immune relevance. Advanced platforms such as genetically engineered mouse models (GEMMs), humanized mi...
Abhishek Sharma, Aman Kumar, Preeti Patel et al.· Advances in Therapy· 0 citations
A nanoemulsion based gel loaded with the β-CD-MTX inclusion complex provides a hopeful approach to enhance topical MTX delivery, improves therapeutic efficacy, and reduces systemic side effects, thereby addressing important limitations of traditional RA therapy.
Aman Kumar, R. Pal, Manish Kumar et al.· BioNanoScience· 1 citation· ⚡1
Genome engineering is evolving from a DNA-cutting system to a precise and programmable genome editing system, which may support the future development of safer and more precise therapeutic strategies.
Vikash Kumar, Aman Kumar, Balak Das Kurmi· Current Pharmacogenomics and...· 0 citations
This chapter highlights the role of targeting ligands, stimuli-responsive systems, and tumor microenvironment-specific strategies in enhancing therapeutic efficacy while minimizing adverse effects, emphasizing the potential of molecularly targeted nanomedicine to advance precision therapy and improve clinical outcomes.
Aman Kumar, Md Hidul Islam, Pranav Dhingra et al.· Advances in Protein Chemistr...· 0 citations
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