Angiography-Derived Versus Wire-Based Physiological Assessment of Intermediate Coronary Lesions—A Non-Inferiority Meta-Analysis and Systematic Review
Background: Wire-based methods-fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are the gold standard for physiological assessment of intermediate coronary lesions, but procedural complexity limits their use. Angiography-derived methods estimate FFR without a pressure wire or hyperemic agent. Direc...