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Author

Alva Annett

2 papers indexed here

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Open access Oct 2026

H3K27M cooperates with ASCL1 to maintain progenitor states and drive gliomagenesis

Histone 3 lysine 27-to-methionine substitutions (H3K27M) drive aggressive diffuse midline gliomas by blocking differentiation of radial glial progenitor cells committed to oligodendrogenesis. We establish prolonged differentiation as a powerful tool to uncover regulators of glioma cell states and demonstrate that t...

Alan L. Jiao, Abolfazl Maghrouni, A. Gutiérrez et al. · 0 citations
Open access Sep 2026

USP15 REGULATES NEUROINFLAMMATION AND DRIVES PATHOGENESIS IN SYNUCLEINOPATHIES

It is shown that ablation of Usp15 in astrocytes and in microglia protects against lethal neuroinflammation in vivo, and a strong cis-acting eQTL directing high USP15 expression in CD14+ myeloid cells is detected in humans.

Nassima Fodil, E. del Cid-Pellitero, V. Piscopo et al. · 0 citations

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