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Author

Alper Bülbül

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Open access Aug 2026

Integrative Multi-Omics Analysis of Multiple Sclerosis Reveals Cell-Type-Specific Regulatory Landscapes and Discordant Methylation–Expression Coupling

These findings nominate MS-relevant regulatory candidates and provide a reusable multi-omics framework for hypothesis generation and validation and nominate two Tier-1 candidates: ITGB2 and IKZF1.

Alper Bülbül, Özdeyiş Hülya Yılmaz-İşgördü, M. Reda et al. · 0 citations
Open access Aug 2026

A Novel Dominantly Segregating PSMB10 Splice-Site Variant in Familial Autoinflammatory Disease with Immunoproteasome and Interferon-Related Dysregulation

The intrafamilial variability observed in this family suggests that additional genetic or immunogenetic factors may modify disease expression, even in autoinflammatory disorders that appear to follow a monogenic inheritance pattern.

U. I. Onat, Alper Bülbül, Dora Sigli et al. · 0 citations

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