Review
Open access
Oct 2026
Natural Bioactive Compounds Targeting the ANGPTL3/4/8 Axis in Dyslipidemia and Cardiometabolic Disease: Molecular Mechanisms, Evidence Hierarchy, and Clinical Translation
Dyslipidemia driven by excess triglyceride-rich lipoproteins (TGRLs) remains a major modifiable determinant of atherosclerotic cardiovascular disease (ASCVD). Over the past decade, the angiopoietin-like protein (ANGPTL) family (specifically ANGPTL3, ANGPTL4, and ANGPTL8) has emerged as a central regulatory axis control...
O. Bolgova, I. Shypilova, Ahmed Yaqinuddin et al.
· Current Issues in Molecular... · 0 citations