Four weeks of romosozumab treatment increases trabecular bone volume and differentially improves cortical bone in young and aging mice with chronic kidney disease
Chronic kidney disease (CKD) leads to significant bone loss and high risk of fractures. Fractures are even more prevalent in the aging population with CKD. Cortical bone is particularly impacted in CKD due to cortical thinning and the development of cortical porosity. The goal of this study was to assess the impact of...