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Author

Allison Heath

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Open access Sep 2026

Proteogenomic analysis of pediatric and AYA high-grade glioma reveals age-dependent biology, female-male differences, and kinase targets.

High-grade gliomas (HGGs) in children and adolescents and young adults (AYA) exhibit distinct biology across the neurodevelopmental spectrum. To dissect tumor-intrinsic molecular characteristics independent of developmental variation, we perform comprehensive proteogenomic analyses of tumors from 112 HGG patients aged...

N. Tignor, M. Koptyra, Shrabanti Chowdhury et al. · 0 citations
Review Aug 2026

Common data element (CDE) and AI-Enabled approaches for clinical data Management: Workshop proceedings from the NIH INCLUDE Project.

OBJECTIVE To evaluate challenges in managing multisite, longitudinal, and multisystem clinical data for Down syndrome (DS) research and identify approaches to improve standardization and reuse. METHODS This report summarizes the outcomes and lessons learned from a NIH workshop convened by the INCLUDE Project to align...

J. Espinosa, Kate Burdekin, J. Auman et al. · 0 citations

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