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Alkinoos A. Armoundas

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Review Aug 2026

Epigenetic Drift and LINE-1 Activation in Aging Brain: Implications for Neurodegenerative Disease.

Findings indicate that impaired epigenetic maintenance, especially in repetitive genome regions, plays a key role in biological aging of neurons and glial cells and the potential of targeting LINE-1 methylation to restore methylation homeostasis, epigenetic stability and delay brain aging.

Alkinoos A. Armoundas, C. Piperi · 0 citations

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