Acquisition of a novel restriction modification system regulates genetic flux and gene expression in the hypervirulent and globally disseminated CC17 lineage of group B Streptococcus
These findings reveal for the first time the importance of restriction modification system activity in defining the lineage structure and virulence potential of group B Streptococcus, uncovering a novel mechanism that underpins the global success of the CC17 clade as a major neonatal pathogen.