Author

Alireza Poustforoosh

2 papers indexed here

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Sep 2026

Uracil-Quinazoline Hybrids: Cytotoxicity, Docking, MD, and DFT Studies.

INTRODUCTION Cancer remains a major cause of mortality worldwide; therefore, research continues to focus on the development of more effective therapeutic agents. METHODS In this study, the cytotoxic effects of a series of uracil-quinazoline hybrids were evaluated against A549 (lung cancer) and HepG2 (hepatocellular c...

Mahkameh Moradimehrabadi, Sara Sadeghian, Alireza Poustforoosh et al. · Medicinal chemistry · 0 citations

Open access Oct 2026

Old Drugs, New Targets: Molecular Docking Insights into Repurposing Proton Pump Inhibitors for the TLR4/MD-2, NLRP3, and C5aR1 Axes in Autoimmune Liver Diseases

Background/Objectives: Autoimmune liver diseases (AILDs), including autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis, may include treatment-resistant cases and therefore require new therapeutic strategies. This in silico study evaluated proton pump inhibitors (PPIs) across three pat...

Mehmet Yıldız, Erdi Şeker, E. Altınkaya et al. · Pharmaceuticals · 0 citations