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Author

Aline Métris

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Review Open access Sep 2026

Methods to Address Compositional Data Challenges in Clinical Studies for the Safety Assessment of Human Microbiome Perturbations.

Advances in sequencing technologies have enabled increasingly detailed characterisation of the human microbiome in clinical studies, but interpretation of microbiome modulation which has relevance to health and disease characterisation or safety assessments remains methodologically challenging. Taxonomic profiles gener...

Aline Métris, Rui Guan, Antonis Ampatzoglou et al. · 0 citations
Open access Jul 2026

Integrating multi-omics data with network modeling to characterize Pseudomonas aeruginosa persister cell metabolism

This study reveals that persister cells retain active metabolism and exhibit a metabolic program distinct from that of untreated cells, and integrated transcriptomics, metabolomics, and genome-scale metabolic modeling to identify specific metabolic pathways that are critical for persister survival.

Joseph M. Ficarrotta, Anna S. Blazier, Aline Métris et al. · 0 citations

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