Author

Alicia Roig-Merino

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Open access Aug 2026

CRISPR/Cas9-based repair of a heterozygous HNF1A mutation in patient-derived hiPSCs

Human induced pluripotent stem cells (hiPSCs) represent a powerful platform for disease modeling, especially in monogenic diseases as they preserve the donor’s genetic background while enabling directed differentiation into disease-relevant cell types. This makes them highly suitable for studying disease mechanisms in...

D. Skoczek, J. Hohendorff, Maciej T. Małecki et al. · Human Genetics · 0 citations