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Author

Ali Bashiri Dezfouli

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Open access Sep 2026

A defined isothiocyanate mixture suppresses platelet signaling and metabolism to limit thrombosis in vivo

Pathological platelet activation drives thrombosis and is a major contributor to morbidity and mortality. Current antiplatelet therapies reduce thrombotic risk but target a limited range of signaling pathways, have minimal impact on established platelet aggregates, and are frequently associated with bleeding complica...

Jan Yağız Buchholz, Maria Shoykhet, Anthea C. Darius et al. · 0 citations
Review Open access Aug 2026

Delineating the CTBP1-Related Phenotypic Spectrum: A Review of HADDTS and Atypical Variants

Hypotonia, Ataxia, Developmental Delay, and Tooth Enamel Defect Syndrome (HADDTS; OMIM #617915) is an ultra-rare autosomal dominant disorder caused by predominantly de novo pathogenic variants in CTBP1, encoding a NAD(H)-dependent transcriptional corepressor. We reviewed all HADDTS cases reported from database inceptio...

E. Akdaş, Dingyu Lu, Linshen Zhang et al. · 0 citations

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