Lipoprotein(a) [Lp(a)] is a genetically determined apolipoprotein B-containing lipoprotein independently associated with atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve stenosis (CAVS). Circulating Lp(a) concentrations are largely inherited, minimally responsive to lifestyle modification, and n...
C. Acierno, D. D'Ardes, A. Boccatonda et al.· Journal of Cardiovascular Ph...· 0 citations
Background/Objectives: Obesity is a major modifiable risk factor for venous thromboembolism (VTE), driven by adipose tissue dysfunction, chronic inflammation, endothelial dysfunction, hypercoagulability, impaired fibrinolysis, immunothrombosis, and venous stasis. Modern incretin-based therapies induce substantial weigh...
Andrea Boccatonda, Alice Brighenti, Alfredo Caturano et al.· Journal of Clinical Medicine· 0 citations
Older adults admitted to internal medicine wards represent a growing population at high risk of sepsis, characterized by frailty, multimorbidity, functional impairment and reduced physiological reserve. While sepsis outcomes have been extensively studied in intensive care settings, less is known about prognostic determ...
M. Sircana, Alfredo Caturano, Mauro Tettamanti et al.· Internal and Emergency Medic...· 0 citations
Cardiometabolic disorders arise from interconnected metabolic, inflammatory, oxidative, mitochondrial, and vascular abnormalities. Lichens produce structurally diverse secondary metabolites, including depsides, depsidones, dibenzofurans, anthraquinones, and other phenolic compounds, whose experimental activities inters...
Alfredo Torres-Benítez, C. Acierno, Davide Nilo et al.· Biomedicines· 0 citations
A narrative review synthesises mechanisms and examines how metformin, glucagon-like peptide-1 receptor agonists, sodium–glucose cotransporter 2 inhibitors and inflammasome-directed agents intersect with them in obesity-associated T2D.
C. Acierno, Massimiliano Cavallo, D. D'Ardes et al.· International Journal of Mol...· 0 citations
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