Author

Alexi Nott

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Open access Sep 2026

Cell type-specific histone acetylation landscape in Alzheimer’s disease reveals a putative role of MITF in microglia

Lysosomal dysfunction and upstream transcriptional regulation via MITF as key processes in AD microglia are implicate in AD pathogenesis.

Charbel Gergian, Paulina Urbanaviciute, Philippa M. Wells et al. · bioRxiv · 0 citations

Open access Jul 2026

A roadmap for enriching rare cell populations from human post-mortem brain, demonstrated by 100% microglial purity

A generalisable roadmap for developing fluorescence-activated nuclear sorting protocols for rare cell populations in human brain is presented, reaching 100% purity in cortex and 98% in cerebellum, with the cortex sort simultaneously yielding astrocytes at 93% purity.

Isidora Gocmanac, Hiranyamaya Dash, M. Weinert et al. · bioRxiv · 0 citations