Open access
Sep 2026
FANCM is required for the PAX3::FOXO1-driven oncogenic program in rhabdomyosarcoma.
Many cancers are driven by mutationally altered transcription factors (TFs) that rewire cells to an oncogenic state. Cells must activate specific mechanisms to tolerate the burden of oncogenic TF activity. To define such mechanisms, we focused on a canonical oncogenic fusion protein-driven cancer, alveolar rhabdomyosar...
C. Delaney, Min Lu, S. Zimmerman et al.
· Cell Reports · 0 citations