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Alexandra-Aurora Dumitra

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Review Open access Aug 2026

From FGFR3 Hyperactivation to Disease-Modifying Therapy in Pediatric Achondroplasia: Molecular Mechanisms, Clinical Evidence, and Emerging Treatments

Achondroplasia is increasingly understood as a disorder of dysregulated growth plate signaling rather than solely a condition of reduced stature and vosoritide provides clinical proof that pharmacological modulation of FGFR3-related signaling can improve growth velocity.

R. Șerban, Andreea-Mădălina Mituț-Velișcu, Alexandra-Aurora Dumitra et al. · 0 citations

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