Author

Alexander V. Kabanov

3 papers indexed here

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Sep 2026

Nanoparticle Co-delivery of Microtubule Inhibitors and Cisplatin Overcomes DNA Repair-Mediated Resistance in Head and Neck Cancer.

Cisplatin remains a crucial chemotherapeutic for head and neck squamous cell carcinoma (HNSCC), but its effectiveness is limited by intrinsic or acquired resistance driven largely by enhanced DNA crosslink repair. Through a combined screen of DNA crosslink repair and cisplatin sensitivity modulators, our current study...

Xin Li, L. Palchak, Ling Wang et al. · Molecular Cancer Therapeutic... · 0 citations

Open access Aug 2026

Poly(2-oxazoline) Micelles for Co-Delivery of Paclitaxel and Metronidazole Benzoate for Dual Chemotherapeutic and Antibacterial Targeting in the Tumor Microenvironment

Tumor-resident pathogenic bacteria can promote cancer progression and reduce chemotherapy efficacy, yet strategies to simultaneously target both tumor cells and intratumoral microbes remain limited. Here, we report a poly(2-oxazoline) micelle (POx) platform co-encapsulating paclitaxel (PTX) and metronidazole benzoate (...

Alyssa Holden, Hallie Hutsell, L. Palchak et al. · Biomedical microdevices · 0 citations

Review Open access Sep 2026

Nanomedicine beyond carriers — devices, cells & living therapeutics

Nanomedicine has progressed far beyond its early role as an experimental drug-carrier toolbox and today stands as a clinically validated enabling technology. Liposomal formulations and albumin-bound nanoparticles have transformed cancer therapy, while lipid nanoparticle (LNP) platforms accelerated the rapid development...

A. Grattoni, Marco M. Paci, Noah Arnold et al. · Biomedical microdevices · 0 citations