Open access
Sep 2026
Nickel electrocatalytic C(sp3)-C(sp3) cross-coupling from activated carboxylic acids and amines.
Carbon-carbon bond-forming reactions are central to medicinal chemistry efforts. Methods that utilise abundant and structurally diverse building blocks can accelerate chemical space exploration in drug discovery. Herein, we report an electrochemical deaminative-decarboxylative cross-coupling reaction to form C(sp3)-C(s...
Bing-Qing Tang, Jennifer Morvan, Filippo Begal et al.
· Organic and biomolecular che... · 0 citations