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Alexander J. Bryer

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Open access Aug 2026

Stoichiometric Binding of Cyclophilin-A to The HIV-1 Capsid Modulates Its Mechanoelastic Properties.

Atomic force microscopy nanoindentation simulations of CypA-decorated capsids reveal that CypA acts as a stoichiometric regulator of capsid mechanical response, highlighting how surface ligand binding programs the mechanical response of protein nanocapsules, offering principles for stimuli-responsive biomolecular mater...

J. Rey, Alexander J. Bryer, J. Perilla · 0 citations

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