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Alessio Di Clemente

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Open access Sep 2026

Prion Protein Deficiency Results in Synaptic, Neural Network and Behavioral Alterations

The cellular form of the prion protein (PrPC) is known for its involvement in the pathogenesis of prion diseases. Recent research implicates the physiological isoform of PrP in neuronal development, excitability, and synaptic plasticity, as well as in other biological processes. However, its precise function in the dev...

Anna Burato, Alessio Di Clemente, Camilla Lodetti et al. · 1 citation
Open access Aug 2026

Minimal Reservoir Computing Generates Hippocampal-Inspired Stimulation for Open-Loop Modulation of Cortical Networks In Vitro.

These results provide an open-loop in vitro proof of concept that a low-event, irregular stimulation schedule can be associated with heterogeneous modulation of cortical-network activity.

Ángel Canal-Alonso, Adam Armada-Moreira, Alessio Di Clemente et al. · 0 citations

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