Open access
Aug 2026
Postnatal Sensory Experience and Barrel Cortex Alterations Anticipate Autistic Traits in a Mouse Model of Cdkl5 Deficiency Disorder.
The data suggest that CDKL5 is required to link tactile processing in the BC to the onset of social interaction abilities, and intriguingly, KO mice show autistic traits at P21 that are ameliorated by neonatal CDKL5 replacement in the BC.
Alessandra Raspanti, R. Pizzo, A. Gurgone et al.
· Progress in neurobiology · 1 citation