Open access
Oct 2026
Tissue-specific deletion of FKBP51 reveals distinct roles in stress responsivity and metabolic regulation
The co-chaperone FKBP51 serves as a critical molecular intersection between environmental stress and metabolic health, yet the specific tissue-level mechanisms driving its systemic effects remain poorly understood. While global FKBP51 deficiency provides robust protection against diet-induced obesity and insulin resist...
M. Springer, L. Brix, V. Kovářová et al.
· Molecular Metabolism · 0 citations