Alesandro Civljak

Broadly reactive antibodies against influenza B virus hemagglutinin neutralize and protect through distinct structural mechanisms

ABSTRACT Influenza B viruses contribute substantially to seasonal disease burden; however, the structural basis by which antibodies recognize the major glycoprotein hemagglutinin (HA) and mediate antiviral activity remains incompletely defined. Influenza B virus used to circulate as two antigenically distinct lineages,...