Open access
Jul 2026
OrgNet+: towards robust protein stability prediction with convolutional neural networks
OrgNet+, a conformational ensemble-aware and orientation-gnostic framework that explicitly incorporates protein structure flexibility during training, is introduced, which substantially reduces intra-ensemble prediction variance while simultaneously improving predictive accuracy.
A. Sarycheva, Aleksandr Shumilov, Petr Popov
· Bioinformatics · 0 citations