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Author

Aleksandar Sič

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2 papers indexed here

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Review Open access Sep 2026

Targeting MicroRNA-21 in Chronic Kidney Disease: Lessons from the Lademirsen Story

MicroRNA-21 (miR-21) has long been regarded as one of the most promising molecular targets in chronic kidney disease (CKD) because of its consistent upregulation across diverse renal disorders and its involvement in fibrosis, inflammation, oxidative stress, and metabolic dysfunction. Strong preclinical evidence demonst...

V. Popović, Aleksandar Sič, Selena Gajić et al. · 0 citations
Review Open access Sep 2026

Neurobiological and Neuroimmune Mechanisms Linking Chronic Pain, Sleep Disturbances and Mental Health Disorders

Chronic pain, sleep disturbances, and mental health disorders such as anxiety and depression disorders frequently co-occur, forming a self-reinforcing cycle that impairs daily functioning and quality of life. Chronic pain is driven by peripheral and central sensitization, the latter sustained by reciprocal microglial–a...

Boris Burnjaković, Harrison Moy, Aleksandar Sič et al. · 0 citations

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