Mechanochemical Hydrazone Synthesis From Isoniazid and Isophthalaldehyde: Kinetics and Process Optimization of a Competitive-Consecutive Reaction.
Mechanochemistry has emerged a greener and more efficient alternative to solution-based methods for hydrazone synthesis. However, prior studies have predominantly focused on final yields, reaction times, and biological activities, while giving limited attention to reaction kinetics and mixing quality effects, which are...