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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Alaa Benachour

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Open access Aug 2026

SERCA is a host target of the SARS-CoV-2 envelope protein linking calcium homeostasis to autophagy

The SARS-CoV-2 envelope (E) protein is a virulence factor that remodels host endomembranes, but mechanisms remain incompletely understood. We recently demonstrated that E protein interacts with and inhibits the sarco/endoplasmic reticulum Ca²⁺-ATPase (SERCA), disrupting ER calcium homeostasis. Here, we investigated how...

Blanka Berta, Sarolta Tóth, P. Lőrincz et al. · 0 citations

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