BACKGROUND
Chronic obstructive pulmonary disease (COPD) is a major global health issue, with pulmonary hypertension (PH) as a severe complication linked to increased morbidity and mortality. Endothelin-1 (ET-1) is a vasoconstrictor peptide and a potential biomarker for PH in COPD due to its role in vascular remodeling...
J. Bajpai, Akshyaya Pradhan, Mohammed Kaleem Ahmad et al.· Annals of African medicine· 0 citations
The results demonstrate that obicetrapib significantly reduces LDL cholesterol by 30–50%, apolipoprotein B by 20–30% and lipoprotein(a) by as much as 40-50%, while elevating HDL cholesterol levels by more than 100%.
P. Thandi, Akshyaya Pradhan, R. Agarwala et al.· European Cardiology· 0 citations
Resistant hypertension (RH) is a high-risk phenotype associated with increased cardiovascular and renal morbidity despite multidrug therapy. Dysregulation of the renin–angiotensin–aldosterone system (RAAS), particularly excess aldosterone activity, plays a central role in the pathophysiology of RH. Although conventiona...
Akshyaya Pradhan, M. Bhandari, Abhishek Singh et al.· Life· 0 citations
