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Author

Akio Kimura

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Case report Open access Aug 2026

Bilateral Orbital Fat Hyperintensity in Early Glial Fibrillary Acidic Protein Astrocytopathy

Objectives Glial fibrillary acidic protein (GFAP) astrocytopathy is an inflammatory autoimmune disease of the CNS that targets astrocytes. Although optic disc edema is a frequently reported ocular manifestation in GFAP astrocytopathy, it has not been well-characterized as orbital fat hyperintensity. Here, we report a r...

Yusuke Ito, K. Ohyama, Akio Kimura et al. · 0 citations
Open access Sep 2026

Characteristics and prognostic factors of cognitive impairment in autoimmune glial fibrillary acidic protein astrocytopathy

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a condition that can occasionally cause cognitive impairment (CI). This study aimed to clarify the characteristics of CI in patients with GFAP-A expression and its associated prognostic factors. This retrospective cohort study included patients diagn...

Yasuko Mori, Akira Takekoshi, Yoya Ono et al. · 0 citations
Review Open access Aug 2026

Delayed appearance of bilateral cerebral peduncle lesions in autoimmune glial fibrillary acidic protein astrocytopathy: A serial MRI case series.

Bilateral cerebral peduncle lesions may represent a delayed non-enhancing MRI manifestation of GFAP-A, and careful assessment of the cerebral peduncles on follow-up MRI may help characterize the evolving lesion distribution.

Yusuke Akitomi, Kensuke Takahashi, Yuta Komori et al. · 0 citations

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