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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Akash G. R.

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Oct 2026

Design and optimization of HME-based floating dolutegravir extrudates with enhanced drug release and potent anti-viral activity.

The hot-melt extrusion (HME) technique is quite successful in improving the solubility and bioavailability of poorly water-soluble drugs. Herein, we report the development of optimized dolutegravir floating systems prepared by the HME technique using Design-Expert software. Optimized parameters for floating extrudate i...

Manisha S. Jain, Akash G. R., B. Gowthami et al. · 0 citations

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