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Author

Aiym Kaiyrlykyzy

2 papers indexed here

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Open access Oct 2026

Gut Microbiome Alterations in Alzheimer’s Disease: A Shotgun Metagenomic Case–Control Study

The gut microbiome has been proposed as a contributor to Alzheimer’s disease (AD) pathogenesis via the microbiota–gut–brain axis, but findings across cohorts are inconsistent and scarce data exist from Central Asian populations. We used shotgun metagenomic sequencing to compare the gut microbiome of AD patients and cog...

A. Issilbayeva, S. Kozhakhmetov, A. Kushugulova et al. · 0 citations
Open access Oct 2026

Genome-Wide Genotype Resource and Exploratory Association Analysis of Alzheimer’s Disease in a Kazakh Population: A Case–Control Study

Background/Objectives: Alzheimer’s disease (AD) has a substantial genetic component, yet Central Asian populations remain markedly underrepresented in genomic studies of the disease. Methods: to address this gap, we generated array-based genotype data using an immune-focused genotyping platform from a Kazakh AD case–co...

Aiym Kaiyrlykyzy, Aygerim Serikzhan, A. Kassenova et al. · 0 citations

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