Aisha Almaghribi

In Silico Pharmacological Evaluation and ADME Profiling of Berberine and Rosmarinic Acid as Potential Inhibitors of Escherichia Coli Dihydrofolate Reductase

Antimicrobial resistance has increased the need to identify alternative antibacterial scaffolds targeting established bacterial pathways. Dihydrofolate reductase (DHFR) is an established antimicrobial target involved in bacterial folate metabolism. This study evaluated selected natural compounds as potential inhibitors...