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Author

Aiqin Shi

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Review Open access Oct 2026

Research progress of SPP1 in cancer regulation: Tumorigenesis, metastasis, tumor microenvironment, immunity and therapeutic targets (Review).

Secreted phosphoprotein 1 (SPP1, also known as osteopontin, OPN) is a multifunctional matricellular glycoprotein that is aberrantly overexpressed in nearly all major human malignancies. It functions as a central signaling hub that drives tumor initiation, sustains cancer stemness, accelerates invasion and metastasis, r...

Yu Xia, Dong Han, Song-Xia Tang et al. · 0 citations
Open access Jul 2026

Protocol for high-resolution mapping of RNA-associated chromatin using chromatin isolation by RNA purification-tag

A protocol for integrating RNA hybridization with in situ tagmentation using chromatin isolation by RNA purification-tag (ChIRP-Tag) is presented, which captures RNA-associated chromatin with high sensitivity and spatial resolution across various cell types.

Ruishuang Fu, Rongjie Zhao, Huimin Yang et al. · 0 citations

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