Plasma P-Tau217 and NfL Longitudinal Changes Across Neurodegenerative Diseases: Impact of α-Synuclein in Alzheimer Disease.
BACKGROUND AND OBJECTIVES Plasma phospho-tau217 (p-tau 217) is a validated biomarker of Alzheimer disease (AD), and its longitudinal dynamics may reflect AD progression. Plasma neurofilament light chain (NfL) reflects axonal injury and neurodegeneration. Their trajectories may be modulated by concomitant proteinopathie...