Metabolomics-based elucidation of the regional difference mechanism of the PPARγ signaling axis in sheep hepatic cystic echinococcosis.
Investigation of metabolic profile alterations and differential regulation of the PPARγ signaling axis in proximal and distal hepatic tissues following E. granulosus infection in sheep elucidated the molecular mechanisms underlying local lipid metabolic reprogramming, providing novel therapeutic targets for metabolic i...